Oncology Research Today is a free monthly online journal that collates and summarizes the latest research about Oncology, including details on cancer, surgery, chemotherapy, radiotherapy.

Developing an oncology portfolio of anticancer drugs: the experience of one pharmaceutical company.

Blackledge GR

AstraZeneca Pharmaceuticals, Macclesfield, UK. George.Blackledge@astrazeneca.com

For a company or institute that wishes to develop new anti-cancer agents, it is necessary to establish a portfolio of agents to reduce the risk of failure. Success rates for developing new agents are low and therefore different biological effect areas should be explored to ensure that at least one agent targeting cancer or a specific histological sub-type of cancer is effectively developed. This paper describes how one pharmaceutical company has developed a range of different agents with the ultimate aim of developing as many of these as is technically feasible into useful new medicines for the treatment of cancer.

Published 12 December 2005 in Zentralbl Gynakol, 127(6): 385-8.
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